everything starts with

One Neuron

Biological Cognition Kernel

From a single cell to a thinking mind. A platform that reproduces
the computational architecture of the biological brain —
not training on data, but learning from experience.

50Hzreal-time
1→5Bneurons
0 GPUrequired

scroll to evolve

architecture

Biological brain on a chip

Pluggable sensors feed the thalamus — the brain's central relay. Specialized regions process, learn, and decide in parallel. Motor outputs drive actions in the physical or digital world.

physical sensors
Camera
Microphone
Lidar / Depth
IMU / Gyroscope
Touch / Pressure
digital sensors
Internet / RSS
LLM Context
Database
API Streams
File System
physical motors
Robotic Actuators
Drone Control
Haptic Feedback
Speaker / Audio
digital motors
HTTP / gRPC
LLM Queries
Database Write
Messaging

Sensory input flows through the thalamus — the brain's relay hub — into specialized cortical and subcortical regions. Each region processes, learns, and feeds decisions back through motor outputs. All connections are bidirectional. All learning is real-time.

progress

From cell to cognition

11 stages · each validated on a biological checkpoint organism

Q3'24 Q4'24 Q1'25 Q4'25 Q1'26 ← now Q3'26 Q4'26 Q1'27 Q2'27 Q3'27 Q4'27
01

The Neuron

Done

A single cell that receives signals, integrates them, and fires. Real membrane dynamics, ion channels, action potentials. 600 million years of evolution begin here.

02

The Synapse

Done

Chemical communication — vesicles release, receptors bind, currents flow. Four receptor types with different speeds create a rich signaling vocabulary.

03

The Circuit

Done

Sensory cells detect, interneurons process, motor neurons act. Excitation and inhibition compete. Reflexes emerge from connectivity.

04

The Connectome

Done

C. elegans · 302 neurons

Complete nervous system mapped from electron microscopy. The agent navigates, learns, adapts in a physics environment.

05

Learning Loops

In Progress

Aplysia · 20K neurons

Reward prediction, temporal credit assignment. The organism learns not just what happened, but when and why.

06

Visual Hierarchy

Q3'26

Drosophila · 140K neurons

Hierarchical object recognition from edges to scenes. Forward models in cerebellum predict action consequences. Cross-modal binding through gamma synchronization.

07

Planning & Reasoning

Q4'26

Bee · 960K neurons

Model-based planning through hippocampal replay. Counterfactual reasoning evaluates unchosen paths. Abstract rules extracted from experience and transferred to novel situations.

08

Self-Model & Metacognition

Q1'27

Mouse · 71M neurons

Integrated self-model with body map, confidence estimation, and cognitive resource allocation. Sleep consolidation optimizes memories. Stress modulates learning. Multi-goal coordination.

09

Theory of Mind

Q2'27

Macaque · 250M neurons

Recursive modeling of others' beliefs and intentions. Tool use to extend capabilities. Social coalitions, deception, and communication signals. Multi-agent coordination.

10

Culture & Recursion

Q3'27

Chimpanzee · 1B neurons

Recursive planning of arbitrary depth. Cultural transmission of knowledge between agents. Composite tool creation. Proto-language with combinatorial signals.

11

Full Cognition

Q4'27

Human-level · 5B bio-eq.

Language as sensorimotor skill. Abstract reasoning over concepts. Meta-learning optimizes learning itself. Autobiographical memory. Volitional control. Scientific reasoning.

specifications
MembraneConductance-based
Rest−70 mV
Threshold−55 mV
Refractory2 ms
specifications
Receptors4 types
Time range2–200 ms
SignalNonlinear conductance
Plasticity9 factors
specifications
LayersSensory → Inter → Motor
SignalsExcitatory + Inhibitory
ComputeWinner-take-all
specifications
Neurons302 (full map)
Synapses~7,000
Senses82 ch / 7 modalities
Motor6 actions
specifications
Scale20,000 neurons
Ganglia5 + 3 modulatory
Plasticity9-factor R-STDP
NeuromodDA, 5-HT, ACh, NE
specifications
Scale140,000 neurons
VisualV1→V2→V4→IT hierarchy
CerebellumForward models
BindingGamma sync
specifications
Scale960,000 neurons
Planning5-10 step lookahead
PFCRule extraction
SpatialN-dimensional maps
specifications
Scale71M neurons
Self-modelBody map + meta
SleepSWR consolidation
GoalsMulti-goal (2-4)
specifications
Scale250M × 4-8 agents
ToMRecursive beliefs
MirrorImitation learning
SocialHierarchy + coalitions
specifications
Scale1B neurons
RecursionArbitrary depth
CultureCross-generation
LanguageCombinatorial signals
specifications
Scale5B bio-equivalent
LanguageEmergent, not trained
ReasoningHypothesis → test
Planning1000+ episode horizon
ChemotaxisHabituationClassical conditioningThermotaxisT-maze decision
Gill-withdrawal reflexSensitizationDishabituationClassical conditioningOperant conditioningReward prediction
Object recognitionOlfactory conditioningMaze navigationOne-shot aversive learningForward predictionHabit formation
Route planningOne-shot learningAbstract rulesCounterfactual reasoningEpisodic future thinkingSun compass navigation
Morris mazeFear conditioningReversal learningHabit formationSleep consolidationStress responseSelf-confidence
Tool useSocial coalitionsDeceptionImitation learningSally-Anne testCommunication signalsSocial hierarchy
Composite tools2nd-order deceptionTeaching by demonstrationCultural traditionsEmpathyProto-language
Scientific reasoningLanguageAbstract analogyMeta-learningAutobiographical memoryCreativityLong-horizon planning
application
MedicineNeural prosthetics
PharmaDrug modeling
BiotechBiomedical implants
application
HardwareNeuromorphic chips
PharmaDrug screening
ResearchMemory research
application
RoboticsMicro-controllers
IndustrialSafety systems
IoTSensor fusion
application
ResearchVirtual organisms
ScienceConnectomics
EdTechEducation
application
RoboticsAdaptive control
LogisticsAutonomous agents
IndustryProcess control
application
Edge AIDevice vision
IndustryPredictive maintenance
MedicalBio-imaging
application
Supply chainLogistics
GamingGame AI
TransportNavigation
application
SafetyUncertainty-aware
R&DDiscovery agents
DevOpsSelf-healing
application
BusinessNegotiation agents
RoboticsCollaborative
HealthAssistive AI
application
EnterpriseKnowledge mgmt
OrgOrganizational AI
R&DAutomation
application
GeneralAutonomous agents
ScienceResearch
CreativeProblem solving

The fundamental building block. We simulate each neuron with biophysically accurate membrane dynamics — not simplified point models, but real conductance-based equations derived from laboratory measurements. Ion channels open and close, currents flow, voltage rises to threshold, and the neuron fires an action potential. This level of fidelity means our neurons respond to inputs exactly as real biological cells do.

For business, this enables accurate drug interaction modeling — predicting how pharmaceutical compounds affect neural activity before clinical trials. Neural prosthetic designers can test electrode interfaces against realistic neuron behavior. Biomedical implant companies get a digital twin of neural tissue.

Neurons don't just pass numbers — they communicate through chemical signals with four distinct receptor types operating on different timescales from 2ms to 200ms. Each synapse adapts its strength based on 9 biological factors: spike timing, activity level, reward, attention, and more. This is real plasticity, not backpropagation.

Neuromorphic chip designers can validate novel architectures against biologically accurate synaptic dynamics. Pharmaceutical companies screen compounds targeting specific receptor types in silico. Memory researchers study how synaptic plasticity creates persistent traces — the physical basis of learning and memory.

When neurons wire together, computation emerges. Sensory neurons detect the environment, interneurons process and filter, motor neurons drive action. Excitatory and inhibitory connections create competition — winner-take-all decisions, lateral inhibition, and reflexes arise from connectivity alone, without explicit programming.

This is the foundation for biological controllers. Micro-robots get reflex-based safety responses that work in real-time without centralized computation. Sensor fusion systems combine multiple input modalities through the same mechanisms that biological organisms use — proven by 600 million years of evolution.

The first complete organism. All 302 neurons of C. elegans wired exactly as mapped from electron microscopy — the only organism whose full nervous system is known to science. The agent lives in a 2D physics sandbox with 82 sensory channels across 7 modalities, and demonstrates 5 validated behaviors that match real laboratory observations.

This is proof that the architecture works end-to-end. For connectomics researchers, it's a living digital model to test hypotheses. For education, it's an interactive neuroscience laboratory. For platform validation, it demonstrates that biological accuracy at the neuron level produces biologically accurate behavior at the organism level.

The organism now learns from experience in real-time. Reward-modulated plasticity means connections strengthen when actions lead to positive outcomes and weaken otherwise. Temporal credit assignment bridges the gap between an action and its delayed consequence — the agent understands not just what happened, but when and why.

For adaptive robotics, this means controllers that improve with every interaction without retraining from scratch. Autonomous agents in warehouses or factories learn optimal paths and procedures on the job. Process control systems predict outcomes and adjust — getting better every hour, not just when an engineer updates the model.

The agent begins to see. A four-level visual hierarchy extracts edges, textures, shapes, and objects — invariant to position and scale. The cerebellum builds forward models that predict what will happen before the agent acts. Basal ganglia learn to automate frequent decisions into fast habits.

Edge-device vision that understands objects, not just pixels — running on CPU without cloud dependencies. Predictive maintenance systems that foresee equipment failure from visual inspection. One-shot aversive learning means a single dangerous event is never repeated. Habit formation automates routine operations, freeing cognitive resources for novel situations.

The agent no longer just reacts — it plans. Hippocampal replay mentally simulates future scenarios before committing. Counterfactual reasoning evaluates paths not taken: 'what if I had gone left instead?' The prefrontal cortex extracts abstract rules from experience and transfers them to entirely new situations.

Logistics systems that optimize multi-stop routes in real-time, adapting to disruptions within seconds. Game AI that plans 5-10 steps ahead and reasons about opponent strategies. Autonomous navigation in novel environments — the agent doesn't need a pre-mapped path, it imagines one. Rule extraction means learning from a few examples generalizes to thousands of cases.

The agent knows what it knows — and what it doesn't. An integrated self-model tracks confidence in every decision. When uncertain, it explores more carefully. Sleep consolidation optimizes memories offline — performance improves after rest. Multiple competing goals are balanced simultaneously.

Uncertainty-aware systems that flag when they're operating outside their training distribution — critical for safety applications. Discovery agents in scientific research that autonomously design experiments to fill knowledge gaps. Self-healing infrastructure that detects degradation, estimates confidence in its diagnosis, and chooses the safest recovery path.

The agent models other minds. It predicts what another agent will do based on that agent's beliefs — even when those beliefs are wrong. It forms coalitions, communicates danger signals, uses tools, and learns by watching others. Multiple agents coordinate in a shared environment.

Negotiation agents that model the counterparty's goals and knowledge to find optimal agreements. Collaborative robots that anticipate human intent and adjust their actions accordingly. Assistive AI that understands what you're trying to do, not just what you said. Multi-agent systems where 4-8 autonomous agents cooperate without centralized coordination.

Plans within plans, to arbitrary depth. Knowledge passes between generations of agents — solutions discovered by one are taught to others through demonstration. Agents create composite tools by combining simpler actions into novel sequences. Proto-language emerges: combinatorial signals that carry meaning.

Knowledge management systems where organizational expertise is captured, transmitted, and improved across teams. R&D automation where agents conduct iterative experiments, learn from each cycle, and teach findings to fresh agents. Education platforms where AI tutors adapt their teaching strategy based on empathy — understanding the student's frustration, confusion, or readiness.

The complete cognitive architecture. Language emerges naturally from sensorimotor experience — not trained on text corpora, but learned the way a child learns: through interaction, imitation, and reward. Abstract reasoning operates over concepts and categories. The agent formulates hypotheses, designs experiments, tests them, and draws conclusions.

General-purpose autonomous agents that handle open-ended tasks across any domain. Scientific research accelerated by AI that generates hypotheses and validates them autonomously. Creative problem solving that produces genuinely novel solutions — not recombinations of training data. All running on a single server, in real-time, with biological fidelity. Not an imitation of intelligence — the real thing.

how it works

Not trained. Embodied.

Unlike LLMs that process text, Cortexy lives inside a body, perceives the world through senses, and learns from every interaction — just like a biological organism.

01

Perceive

The agent senses the world through multiple modalities — vision, touch, smell, temperature, sound. The same channels biological organisms use to understand their environment.

02

Process

Biologically accurate neurons fire and communicate. Specialized brain regions process signals in parallel — each optimized for its function, working together as a whole.

03

Decide

Multiple systems compete and cooperate. Risk is weighed, plans are formed, habits are triggered. Decisions emerge from the interaction — not from a single algorithm.

04

Act

Actions drive physical or digital outputs. Consequences are predicted before execution. Every action changes the environment — creating new input for the next cycle.

05

Learn

Reward signals strengthen successful pathways. Multiple biological factors shape every connection in real-time. No retraining needed. The system adapts continuously.

06

Remember

Episodes are stored and indexed. Offline consolidation replays and optimizes memories. Experience accumulates — the agent improves with every hour of operation.

Traditional AI

  • Trained on static datasets
  • No body, no senses
  • Frozen after training
  • GPU clusters required
  • Predicts text, not actions

Cortexy

  • Learns from experience
  • Embodied, multi-sensory
  • Adapts in real-time
  • Runs on CPU
  • Perceives, decides, acts

connectivity

Universal Plugin Protocol

The brain connects to the world through a standardized binary protocol. Any sensor or motor — physical or digital — plugs in with a single interface. Swap a camera for a lidar. Replace robotic actuators with API calls. The brain doesn't know the difference.

Hot-swappable

Add or remove sensors and motors at runtime. The brain automatically adapts its sensory map and motor repertoire.

Universal interface

One protocol for everything — from a $5 temperature sensor to a million-dollar robotic arm. Same binary format, same manifest, same channel system.

Zero configuration

Plugins self-describe through manifests. The brain discovers available channels, allocates neural pathways, and starts processing — automatically.

performance

Real-time on commodity hardware

No GPU clusters. No cloud dependencies. The entire cognitive architecture runs on a single server — from perception through decision to action — 50 times per second.

50Hz Real-time loop

Brain, physics, and senses fully synchronized. Every 20ms a complete cognitive cycle — perceive, process, decide, act.

<1ms Per decision cycle

Perception to action in under a millisecond. The remaining 19ms is headroom for learning, memory consolidation, and planning.

0 GPU CPU-only execution

Event-driven architecture means only active neurons compute. Silent neurons cost zero. Standard CPU hardware, no specialized accelerators.

5B Neurons on one server

Human-scale cognition on a single 4-socket server. Columnar compression achieves 100× memory efficiency over traditional neuron-by-neuron simulation.

Get in touch

Interested in the project? Have questions about the technology?
We'd love to hear from you.

hello@cortexy.dev